Chromosome movements promoted by the mitochondrial protein SPD-3 are required for homology search during Caenorhabditis elegans meiosis.
Pairing of homologous chromosomes during early meiosis is essential to prevent the formation of aneuploid gametes.Chromosome pairing includes a step of homology search followed by the stabilization of homolog interactions by the synaptonemal complex (SC).These events coincide with dramatic changes in nuclear organization and rapid chromosome moveme